Human genetics of Buruli ulcer

  title={Human genetics of Buruli ulcer},
  author={J{\'e}r{\'e}my Manry},
  journal={Human Genetics},
  • J. Manry
  • Published 7 April 2020
  • Biology, Medicine
  • Human Genetics
Buruli ulcer, the third most common mycobacterial disease worldwide, is caused by Mycobacterium ulcerans and characterized by devastating necrotizing skin lesions. Susceptibility to Buruli ulcer is thought to depend on host genetics, but very few genetic studies have been performed. The identification of a microdeletion on chromosome 8 in a familial form of severe Buruli ulcer suggested a monogenic basis of susceptibility. The role of common host genetic variants in Buruli ulcer development has… 
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Buruli Ulcer: a Review of the Current Knowledge
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