Human gastric tissues simultaneously express the classical and alternative splicing cholecystokinin-B/gastrin receptors.

@article{Zhou2004HumanGT,
  title={Human gastric tissues simultaneously express the classical and alternative splicing cholecystokinin-B/gastrin receptors.},
  author={Jianjiang Zhou and Manling Chen and Qunzhou Zhang and Jian-kun Hu and Wenling Wang},
  journal={Receptors & channels},
  year={2004},
  volume={10 5-6},
  pages={185-8}
}
To explore whether cholecystokinin-B/gastrin receptor (CCKBRwt) gene and its alternative splicing variant preserving intron 4 (CCKBRi4sv) are expressed in human gastric carcinoma cell line and tissue, we detect mRNA expression of CCKBRwt and CCKBRi4sv in 30 gastric carcinoma and their corresponding normal tissues, 10 gastritis, and 2 autopsied normal stomach specimens as well as in a gastric carcinoma cell line SGC-7901 cells by RT-PCR and sequencing. The results revealed that human normal… CONTINUE READING