Human gamma-glutamyl hydrolase: cloning and characterization of the enzyme expressed in vitro.

@article{Yao1996HumanGH,
  title={Human gamma-glutamyl hydrolase: cloning and characterization of the enzyme expressed in vitro.},
  author={R. Yao and E. Schneider and T. Ryan and J. Galivan},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1996},
  volume={93 19},
  pages={
          10134-8
        }
}
  • R. Yao, E. Schneider, +1 author J. Galivan
  • Published 1996
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
A cDNA encoding human gamma-glutamyl hydrolase has been identified by searching an expressed sequence tag data base and using rat gamma-glutamyl hydrolase cDNA as the query sequence. The cDNA encodes a 318-amino acid protein of Mr 35,960. The deduced amino acid sequence of human gamma-glutamyl hydrolase shows 67% identity to that of rat gamma-glutamyl hydrolase. In both rat and human the 24 amino acids preceding the N terminus constitute a structural motif that is analogous to a leader or… Expand
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