Human galectin-3 selective and high affinity inhibitors. Present state and future perspectives.

@article{TllezSanz2013HumanGS,
  title={Human galectin-3 selective and high affinity inhibitors. Present state and future perspectives.},
  author={Ramiro T{\'e}llez-Sanz and Lu{\'i}s Garc{\'i}a-Fuentes and Antonio Vargas-Berenguel},
  journal={Current medicinal chemistry},
  year={2013},
  volume={20 24},
  pages={
          2979-90
        }
}
Over the last decade an increasing number of studies have been published reporting on the inhibitory potency or selectivity that several types of ligands show against human galectin-3 (hGal-3). The reason for this interest lies in the many important roles galectins play both in intra and extra-cellular functions. Among galectins, galectin-3 stands out because it is the only known member of its subfamily in mammals, is small and monomeric but capable of aggregating, and is known to be involved… CONTINUE READING