Human epilepsies: interaction of genetic and acquired factors

@article{Berkovic2006HumanEI,
  title={Human epilepsies: interaction of genetic and acquired factors},
  author={S. Berkovic and J. Mulley and I. Scheffer and S. Petrou},
  journal={Trends in Neurosciences},
  year={2006},
  volume={29},
  pages={391-397}
}
  • S. Berkovic, J. Mulley, +1 author S. Petrou
  • Published 2006
  • Medicine
  • Trends in Neurosciences
  • Epilepsies, once regarded as due to demoniacal possession, can have both genetic and acquired causes, with interaction of these factors in many cases. To date, nearly all the genes discovered to be involved in human epilepsies encode subunits of ion channels, both voltage-gated and ligand-gated. Established acquired causes include serious brain trauma, stroke, tumours and infective lesions. Thus, in terms of exploring the neurobiology of "nature and nurture" in disease, the epilepsies are an… CONTINUE READING

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 50 REFERENCES