Human eosinophils produce and release a novel chemokine, CCL23, in vitro.

@article{Matsumoto2011HumanEP,
  title={Human eosinophils produce and release a novel chemokine, CCL23, in vitro.},
  author={Kenji Matsumoto and Shuhei Fukuda and Noriko Hashimoto and Hirohisa Saito},
  journal={International archives of allergy and immunology},
  year={2011},
  volume={155 Suppl 1},
  pages={34-9}
}
BACKGROUND CCL23 (MPIF1/CK-BETA-8) is a novel CC chemokine that plays important roles in the inhibition of myeloid progenitor cell development, the selective recruitment of resting T lymphocytes and monocytes, and the potentiation of VEGF-induced proliferation and migration of human endothelial cells. Since eosinophils participate in the pathogenesis of airway remodeling, we examined CCL23 production and release by human eosinophils in vitro. METHODS Using Ficoll and antibody-coated… CONTINUE READING