Human enterocyte (Caco-2) migration is modulated in vitro by extracellular matrix composition and epidermal growth factor.


The modulation of enterocyte sheet migration was studied using Caco-2 cells, a well-differentiated human colonic cell line. Although Caco-2 cells attached and spread equivalently over collagen types I, III, IV, and V and laminin, migration over laminin was significantly slower than migration over the collagen types. Fibronectin was a poor substrate for… (More)


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