Human endogenous retrovirus-R Env glycoprotein as possible autoantigen in autoimmune disease.


It has long been discussed whether endogenous retroviruses (ERVs) are involved in the pathogenesis of autoimmune diseases. Among various human endogenous retroviruses (HERVs), we have focused on HERV-R. To investigate the biological roles of HERV-R, we earlier established transgenic rats carrying the full sequence of the viral genome. In these HERV-R rats… (More)
DOI: 10.1089/aid.2009.0048

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