Human endogenous retrovirus K (HERV-K) is expressed in villous and extravillous cytotrophoblast cells of the human placenta.

@article{Kaemmerer2011HumanER,
  title={Human endogenous retrovirus K (HERV-K) is expressed in villous and extravillous cytotrophoblast cells of the human placenta.},
  author={Ulrike Kaemmerer and Ariane Germeyer and Sven Stengel and Michaela Kapp and Joachim Denner},
  journal={Journal of reproductive immunology},
  year={2011},
  volume={91 1-2},
  pages={1-8}
}
Human endogenous retroviruses (HERVs) have been shown to be important in physiological and pathophysiological processes in humans. Several HERVs have been found to be expressed in the placenta-a tissue with special immunomodulatory functions that is responsible for nutrition of the embryo and the ability of the semiallogenic trophoblast to invade. The envelope proteins of HERV-W (also known as syncytin 1) and HERV-FRD (syncytin 2) were shown to be involved in cell fusion leading to the… CONTINUE READING
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