Human endogenous retrovirus HERV-K14 families: status, variants, evolution, and mobilization of other cellular sequences.

@article{Flockerzi2005HumanER,
  title={Human endogenous retrovirus HERV-K14 families: status, variants, evolution, and mobilization of other cellular sequences.},
  author={Aline Flockerzi and Stefan Burkhardt and Werner Schempp and Eckart Meese and Jens Mayer},
  journal={Journal of virology},
  year={2005},
  volume={79 5},
  pages={
          2941-9
        }
}
The human genome harbors many distinct families of human endogenous retroviruses (HERVs) that stem from exogenous retroviruses that infected the germ line millions of years ago. Many HERV families remain to be investigated. We report in the present study the detailed characterization of the HERV-K14I and HERV-K14CI families as they are represented in the human genome. Most of the 68 HERV-K14I and 23 HERV-K14CI proviruses are severely mutated, frequently displaying uniform deletions of… CONTINUE READING

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