Human emotion and memory: interactions of the amygdala and hippocampal complex

@article{Phelps2004HumanEA,
  title={Human emotion and memory: interactions of the amygdala and hippocampal complex},
  author={Elizabeth A. Phelps},
  journal={Current Opinion in Neurobiology},
  year={2004},
  volume={14},
  pages={198-202}
}
  • E. Phelps
  • Published 1 April 2004
  • Psychology, Biology
  • Current Opinion in Neurobiology

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References

SHOWING 1-10 OF 48 REFERENCES
Encoding of emotional memories depends on amygdala and hippocampus and their interactions
TLDR
Data indicate a reciprocal dependence between amygdala and hippocampus during the encoding of emotional memories in patients with variable degrees of left hippocampal and amygdala pathology who performed a verbal encoding task during functional magnetic resonance imaging.
Amygdala activity related to enhanced memory for pleasant and aversive stimuli
TLDR
It is shown that bilateral amygdala activity during memory encoding is correlated with enhanced episodic recognition memory for both pleasant and aversive visual stimuli relative to neutral stimuli, and that this relationship is specific to emotional stimuli.
Event-Related Activation in the Human Amygdala Associates with Later Memory for Individual Emotional Experience
TLDR
The view that amygdala activation reflects moment-to-moment subjective emotional experience and that this activation enhances memory in relation to the emotional intensity of an experience is supported.
Arousal-Mediated Memory Consolidation: Role of the Medial Temporal Lobe in Humans
TLDR
A group difference in the effect of arousal on the rate of forgetting suggests that the role of medial temporal lobe structures in memory consolidation for arousing events is conserved across species.
The amygdala: vigilance and emotion
TLDR
A review of available studies examining the human amygdala covers both lesion and electrical stimulation studies as well as the most recent functional neuroimaging studies, and attempts to integrate basic information on normal amygdala function with the current understanding of psychiatric disorders, including pathological anxiety.
The amygdala's role in long-term declarative memory for gist and detail.
TLDR
Preliminary support is provided for the idea that the amygdala may help filter the encoding of relevant information from stimuli that signal threat or danger in long-term declarative memory for those stimuli.
Impaired emotional declarative memory following unilateral amygdala damage.
TLDR
It is suggested that the normal facilitation of memory for emotional stimuli may develop over an extended time course, consistent with prior findings, and that the specific impairment reported may depend in part on the lexical nature of the task used (written questionnaire).
Sex-Related Difference in Amygdala Activity during Emotionally Influenced Memory Storage
TLDR
Results demonstrate a clear gender-related lateralization of amygdala involvement in emotionally influenced memory, and indicate that theories of the neurobiology of emotionally influencing memory must begin to account for the influence of gender.
Rethinking Feelings: An fMRI Study of the Cognitive Regulation of Emotion
TLDR
Functional magnetic resonance imaging findings support the hypothesis that prefrontal cortex is involved in constructing reappraisal strategies that can modulate activity in multiple emotion-processing systems.
...
...