Human embryonic stem cells and cardiac repair.

  title={Human embryonic stem cells and cardiac repair.},
  author={W Zhu and Kip D. Hauch and Chunhui Xu and Michael A. Laflamme},
  journal={Transplantation reviews},
  volume={23 1},
The muscle lost after a myocardial infarction is replaced with noncontractile scar tissue, often initiating heart failure. Whole-organ cardiac transplantation is the only currently available clinical means of replacing the lost muscle, but this option is limited by the inadequate supply of donor hearts. Thus, cell-based cardiac repair has attracted considerable interest as an alternative means of ameliorating cardiac injury. Because of their tremendous capacity for expansion and unquestioned… CONTINUE READING