Human embryonal extracts modulate placental function in the first trimester: effects of visceral tissues upon chorionic gonadotropin and progesterone secretion.

@article{Barnea1989HumanEE,
  title={Human embryonal extracts modulate placental function in the first trimester: effects of visceral tissues upon chorionic gonadotropin and progesterone secretion.},
  author={Eytan R. Barnea and Ronald J. Simon and S Kol},
  journal={Placenta},
  year={1989},
  volume={10 4},
  pages={331-44}
}
We investigated the effect of human first trimester fetal visceral organ extracts upon placental function, as evidenced by secretion of human chorionic gonadotropin and progesterone in explant cultures of 7-10 weeks gestational age trophoblast. Certain alcohol/water or water extracted embryonal tissues, in highly diluted solutions (1:100-1:2,000 final) had significant effects upon secretion of both hormones. The alcohol/water extract produced an opposite effect. This inhibitory effect was also… CONTINUE READING