Human early fracture hematoma is characterized by inflammation and hypoxia.

@article{Kolar2011HumanEF,
  title={Human early fracture hematoma is characterized by inflammation and hypoxia.},
  author={Paula Kolar and Timo Gaber and Carsten Perka and Georg N. Duda and Frank Buttgereit},
  journal={Clinical orthopaedics and related research},
  year={2011},
  volume={469 11},
  pages={3118-26}
}
BACKGROUND An effective immune system, especially during the inflammatory phase, putatively influences the quality and likelihood of bone healing. If and how this is reflected within the initial fracture hematoma is unclear. QUESTIONS/PURPOSES We therefore asked the following questions: (1) Does the local expression in fracture hematoma of genes involved in adaptation to hypoxia, migration, angiogenesis, and osteogenesis vary as compared to the peripheral blood? (2) Do these changes occur… CONTINUE READING
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