Human dopamine beta-hydroxylase (DBH) regulatory polymorphism that influences enzymatic activity, autonomic function, and blood pressure.

Abstract

RATIONALE Dopamine beta-hydroxylase (DBH) plays an essential role in catecholamine synthesis by converting dopamine into norepinephrine. Here we systematically investigated DBH polymorphisms associated with enzymatic activity as well as autonomic and blood pressure (BP)/disease phenotypes in vivo. METHODS AND RESULTS Seventy genetic variants were… (More)
DOI: 10.1097/HJH.0b013e328332bc87

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Cite this paper

@article{Chen2010HumanDB, title={Human dopamine beta-hydroxylase (DBH) regulatory polymorphism that influences enzymatic activity, autonomic function, and blood pressure.}, author={Yuqing Chen and Gen Wen and Fangwen Rao and Kuixing Zhang and Lei Wang and Juan L. Rodr{\'i}guez-Flores and Amber Paratore Sanchez and Manjula Mahata and Laurent Taupenot and Ping Sun and Sushil K Mahata and Bamidele O Tayo and Nicholas J. Schork and Michael Ziegler and Bruce A Hamilton and Daniel T. O'Connor}, journal={Journal of hypertension}, year={2010}, volume={28 1}, pages={76-86} }