Human diseases reveal novel roles for neural laminins

  title={Human diseases reveal novel roles for neural laminins},
  author={Holly Colognato and Charles ffrench-Constant and Maria Laura Feltri},
  journal={Trends in Neurosciences},
Extracellular matrix molecules such as laminins have a central role in regulating cell behaviour. However, our understanding of their functions in the mammalian nervous system is incomplete. It is important to establish these functions, both for an understanding of normal development and to devise strategies to enhance repair. Here, we review how insights gained from human diseases caused by genetic mutations in laminins or their receptors have revealed significant and sometimes unexpected… CONTINUE READING

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Extracellular matrix: functions in the nervous system.

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