Human detrusor smooth muscle cells release interleukin-6, interleukin-8, and RANTES in response to proinflammatory cytokines interleukin-1beta and tumor necrosis factor-alpha.

@article{Bouchelouche2006HumanDS,
  title={Human detrusor smooth muscle cells release interleukin-6, interleukin-8, and RANTES in response to proinflammatory cytokines interleukin-1beta and tumor necrosis factor-alpha.},
  author={Kirsten Bouchelouche and Susana {\'A}lvarez and Thomas Horn and Jorgen Nordling and Pierre Nourdine Bouchelouche},
  journal={Urology},
  year={2006},
  volume={67 1},
  pages={214-9}
}
OBJECTIVES Recently, we have demonstrated that human detrusor smooth muscle cells in culture secrete the chemokine monocyte chemoattractant protein 1. In the present study, we extended these studies to include the effect of the proinflammatory cytokines tumor necrosis factor (TNF)-alpha and interleukin (IL)-1beta on IL-8, IL-6, and RANTES (regulated on activation, normal T cell expressed and secreted) release by human detrusor smooth muscle cells (HDSMCs) and examined their regulation… CONTINUE READING
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