Human dendritic cells express the IL-18R and are chemoattracted to IL-18.

@article{Gutzmer2003HumanDC,
  title={Human dendritic cells express the IL-18R and are chemoattracted to IL-18.},
  author={Ralf Gutzmer and Katja Langer and Susanne Mommert and Miriam Wittmann and Alexander Kapp and Thomas T Werfel},
  journal={Journal of immunology},
  year={2003},
  volume={171 12},
  pages={6363-71}
}
IL-18 is secreted by a variety of cells such as epithelial cells, macrophages, and dendritic cells (DC), in particular, in areas of chronic inflammation. The effects of IL-18 are complex and not fully understood thus far. We sought to explore human DC as a new target for IL-18, since IL-18R expression has been described on myeloid cells such as macrophages… CONTINUE READING