Human dendritic cell subsets and function in health and disease

@article{Okeeffe2015HumanDC,
  title={Human dendritic cell subsets and function in health and disease},
  author={Meredith O’keeffe and Wai Hong Mok and K. Jim Radford},
  journal={Cellular and Molecular Life Sciences},
  year={2015},
  volume={72},
  pages={4309-4325}
}
The method of choice for the development of new vaccines is to target distinct dendritic cell subsets with antigen in vivo and to harness their function in situ to enhance cell-mediated immunity or induce tolerance to specific antigens. The innate functions of dendritic cells themselves may also be targeted by inhibitors or activators that would target a specific function such as interferon production, potentially important in autoimmune disease and chronic viral infections. Importantly… CONTINUE READING
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