Human decidual macrophages and NK cells differentially express Toll-like receptors and display distinct cytokine profiles upon TLR stimulation

@inproceedings{Duriez2014HumanDM,
  title={Human decidual macrophages and NK cells differentially express Toll-like receptors and display distinct cytokine profiles upon TLR stimulation},
  author={Marion Duriez and H{\'e}lo{\"i}se Quillay and Yoann Madec and Hicham El Costa and Claude Cannou and Romain Marlin and Claire de Truchis and Mona Rahmati and Françoise Barr{\'e}-Sinoussi and M. T. Nugeyre and Elisabeth Menu},
  booktitle={Front. Microbiol.},
  year={2014}
}
Maternofetal pathogen transmission is partially controlled at the level of the maternal uterine mucosa at the fetal implantation site (the decidua basalis), where maternal and fetal cells are in close contact. Toll-like receptors (TLRs) may play an important role in initiating rapid immune responses against pathogens in the decidua basalis, however the tolerant microenvironment should be preserved in order to allow fetal development. Here we investigated the expression and functionality of TLRs… CONTINUE READING
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