Human cytomegalovirus strain Towne glycoprotein B is processed by proteolytic cleavage.

@article{Spaete1988HumanCS,
  title={Human cytomegalovirus strain Towne glycoprotein B is processed by proteolytic cleavage.},
  author={Richard R Spaete and Richard H. Thayer and William S. Probert and Frank R. Masiarz and Scott H. Chamberlain and Lynn Rasmussen and Thomas C. Merigan and C A Pachl},
  journal={Virology},
  year={1988},
  volume={167 1},
  pages={207-25}
}
The gene encoding glycoprotein B of human cytomegalovirus (CMV) strain Towne was cloned, sequenced, and expressed in order to study potential targets for viral neutralization. Secondary structure analysis of the 907 amino acid protein predicted a 24 amino acid N-terminal signal sequence and a potential transmembrane region composed of two domains, 34 and 21 amino acids. The CMV (Towne) gB gene had a 94% nucleotide similarity and a 95% amino acid similarity to the CMV (AD169) gB gene [as… CONTINUE READING

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