Human cytomegalovirus-specific T cell reconstitution in young patients receiving T cell-depleted, allogeneic hematopoietic stem cell transplantation.

@article{Lilleri2009HumanCT,
  title={Human cytomegalovirus-specific T cell reconstitution in young patients receiving T cell-depleted, allogeneic hematopoietic stem cell transplantation.},
  author={Daniele Lilleri and Giuseppe Gerna and Chiara Fornara and Antonella Chiesa and Giuditta Comolli and Marco Zecca and Franco Locatelli},
  journal={The Journal of infectious diseases},
  year={2009},
  volume={199 6},
  pages={829-36}
}
BACKGROUND Reconstitution of human cytomegalovirus (HCMV) T cell-specific immunity is of crucial relevance in patients receiving a hematopoietic stem cell transplant (HSCT). Scarce data on this subject are available for children receiving a T cell-depleted HSCT. METHODS We investigated HCMV-specific T cell recovery in 48 recipients of a T cell-depleted HSCT from a human leukocyte antigen (HLA)-disparate relative. Autologous HCMV-infected dendritic cells were used to stimulate HCMV-specific… CONTINUE READING
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