Human cytomegalovirus mediates cell cycle progression through G(1) into early S phase in terminally differentiated cells.

@article{Sinclair2000HumanCM,
  title={Human cytomegalovirus mediates cell cycle progression through G(1) into early S phase in terminally differentiated cells.},
  author={John Sinclair and Joan Baillie and Leesa Bryant and Richard Caswell},
  journal={The Journal of general virology},
  year={2000},
  volume={81 Pt 6},
  pages={1553-65}
}
Terminal differentiation of embryonal carcinoma cells and monocytes has been shown to be important for their permissiveness for human cytomegalovirus (HCMV) infection, even though such terminally differentiated cells have withdrawn from the cell cycle and are, essentially, in G(0) arrest. Recently, data from a number of laboratories have shown that productive infection with HCMV of quiescent fibroblasts held reversibly in G(0) of the cell cycle can result in cell cycle progression, which… CONTINUE READING

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