Human cytomegalovirus increases HUVEC sensitivity to thrombin and modulates expression of thrombin receptors

@article{Popovic2010HumanCI,
  title={Human cytomegalovirus increases HUVEC sensitivity to thrombin and modulates expression of thrombin receptors},
  author={Milan Popovic and Svetlana D. Paskas and Maja Lj Živkovi{\'c} and Ladislav Burysek and Yves Laumonnier},
  journal={Journal of Thrombosis and Thrombolysis},
  year={2010},
  volume={30},
  pages={164-171}
}
Human cytomegalovirus (HCMV) establishes a life-long persistent infection. HCMV infection could be associated with chronic inflammatory diseases, such as cardiovascular disease and atherosclerosis. Here we observed that in HCMV (AD-169) pre-exposed human umbilical vein endothelial cells (HUVEC), thrombin-induced expression of IL-1α and M-CSF is markedly… CONTINUE READING