Human cytomegalovirus carries serine/threonine protein phosphatases PP1 and a host-cell derived PP2A.

@article{Michelson1996HumanCC,
  title={Human cytomegalovirus carries serine/threonine protein phosphatases PP1 and a host-cell derived PP2A.},
  author={Susan Michelson and Patric Turowski and Laurent Picard and Jozef Goris and Maria Paola Landini and A Topilko and Brian Hemmings and Christine Bessia and Alphonse Garc{\'i}a and J. L. Virelizier},
  journal={Journal of virology},
  year={1996},
  volume={70 3},
  pages={1415-23}
}
Human cytomegalovirus (CMV), a herpesvirus, is an important cause of morbidity and mortality in immunocompromised patients. When studying hyper-immediate-early events after contact between CMV virions and the cell membrane, we observed a hypophosphorylation of cellular proteins within 10 min. This can be explained in part by our finding that purified CMV contains serine/threonine protein phosphatase activities. Biochemical analyses indicate that this protein phosphatase activity has all… CONTINUE READING
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Multidisciplinary approach to understanding cytomegalovirus disease, p. 1–12

  • M. F. Stinski, M. P. Macias, C. L. Malone
  • 1995
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