Human corpus callosum in aging and Alzheimer's disease: a magnetic resonance imaging study.

@article{Biegon1994HumanCC,
  title={Human corpus callosum in aging and Alzheimer's disease: a magnetic resonance imaging study.},
  author={Anat Biegon and J. L. Eberling and Bruce C. Richardson and M. Serote Roos and Stephen T. G. Wong and Bruce R. Reed and William J. Jagust},
  journal={Neurobiology of aging},
  year={1994},
  volume={15 4},
  pages={393-7}
}
The involvement of the corpus callosum in aging and Alzheimer's disease (AD) is not clear. We measured cross sectional areas of the entire corpus callosum (CC), as well as the front 20% (genu), middle 60% (body), and posterior 20% (splenium) of the structure from a midsagittal MRI slice in AD patients (N = 20), and young (N = 16) and old (N = 13) control subjects. We found that mean CC area in young controls was 570 +/- 107 mm2. Aging did not significantly affect the mean area of the CC (562… CONTINUE READING
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