Human cord blood-derived platelet lysate enhances the therapeutic activity of adipose-derived mesenchymal stromal cells isolated from Crohn’s disease patients in a mouse model of colitis

@inproceedings{Forte2015HumanCB,
  title={Human cord blood-derived platelet lysate enhances the therapeutic activity of adipose-derived mesenchymal stromal cells isolated from Crohn’s disease patients in a mouse model of colitis},
  author={Dorian Forte and Marilena Ciciarello and Maria Chiara Valerii and Luigia De Fazio and Elena Cavazza and Rosaria Giordano and Valentina Parazzi and Lorenza Lazzari and Silvio Laureti and Fernando Rizzello and Michele Cavo and Antonio Curti and Roberto Massimo Lemoli and Enzo Spisni and Lucia Catani},
  booktitle={Stem Cell Research & Therapy},
  year={2015}
}
Due to their immunomodulatory properties, mesenchymal stromal cells (MSCs) have been used for auto-immune disease treatment. Crohn disease (CD) and ulcerative colitis are two major inflammatory bowel diseases (IBDs), resulting from pathological immune responses to environmental or microbial antigens. Preclinical and clinical studies have suggested that MSC… CONTINUE READING