Human circulating AC133(+) stem cells restore dystrophin expression and ameliorate function in dystrophic skeletal muscle.

@article{Torrente2004HumanCA,
  title={Human circulating AC133(+) stem cells restore dystrophin expression and ameliorate function in dystrophic skeletal muscle.},
  author={Yvan Torrente and Marzia Laura Chiara Belicchi and Maurilio Sampaolesi and Federica Pisati and Mirella Meregalli and Giuseppe D'Antona and Rossana Tonlorenzi and Laura Porretti and Manuela Gavina and Kamel Mamchaoui and Maria Antonietta Pellegrino and Denis Furling and Vincent Mouly and Gillian Butler-Browne and Roberto Bottinelli and Giulio Cossu and Nereo Bresolin},
  journal={The Journal of clinical investigation},
  year={2004},
  volume={114 2},
  pages={182-95}
}
Duchenne muscular dystrophy (DMD) is a common X-linked disease characterized by widespread muscle damage that invariably leads to paralysis and death. There is currently no therapy for this disease. Here we report that a subpopulation of circulating cells expressing AC133, a well-characterized marker of hematopoietic stem cells, also expresses early… CONTINUE READING