Human chorionic gonadotrophin regulates FGF2 and other cytokines produced by human endometrial epithelial cells, providing a mechanism for enhancing endometrial receptivity.

@article{Paiva2011HumanCG,
  title={Human chorionic gonadotrophin regulates FGF2 and other cytokines produced by human endometrial epithelial cells, providing a mechanism for enhancing endometrial receptivity.},
  author={Premila Paiva and Natalie J Hannan and Cassandra L. Hincks and Katie L Meehan and Enid Pruysers and Evdokia Dimitriadis and Lois A. Salamonsen},
  journal={Human reproduction},
  year={2011},
  volume={26 5},
  pages={1153-62}
}
BACKGROUND Preimplantation cross-talk between a functional blastocyst and the endometrium is critical for successful blastocyst implantation. This interaction is mediated in part by endometrial cytokines/growth factors secreted by glandular epithelium into the uterine cavity. Recent evidence suggests that blastocyst-derived hCG may influence the endometrial milieu in conception cycles thereby enhancing receptivity and implantation success. This study investigated the effect of hCG on the… CONTINUE READING