Human choriocarcinoma JAR cells constitutively express pro-interleukin-1beta that can be released with Fc(gamma) receptor engagement.

@article{Jarvis1998HumanCJ,
  title={Human choriocarcinoma JAR cells constitutively express pro-interleukin-1beta that can be released with Fc(gamma) receptor engagement.},
  author={James N. Jarvis and Changsheng Xu and Liqing Zhao and Madonna Iobidze and Heide T. Moore},
  journal={Pediatric research},
  year={1998},
  volume={43 4 Pt 1},
  pages={
          509-13
        }
}
Some authors have suggested that fetally derived syncytiotrophoblasts, which form the barrier between mother and the fetus, are an integral part of a complex macrophage-cytokine network involving maternal leukocytes, decidual cells, placental tissues, and even the fetus itself. We report here that syncytiotrophoblast-like JAR cells, a human choriocarcinoma cell line, share another feature common to cells of the monocyte-macrophage lineage, the ability to secrete IL-1beta when stimulated through… CONTINUE READING