Human chondrosarcoma secretes vascular endothelial growth factor to induce tumor angiogenesis and stores basic fibroblast growth factor for regulation of its own growth.

@article{Furumatsu2002HumanCS,
  title={Human chondrosarcoma secretes vascular endothelial growth factor to induce tumor angiogenesis and stores basic fibroblast growth factor for regulation of its own growth.},
  author={Takayuki Furumatsu and Keiichiro Nishida and Akira Kawai and Masayoshi Namba and Hajime Inoue and Yoshifumi Ninomiya},
  journal={International journal of cancer},
  year={2002},
  volume={97 3},
  pages={313-22}
}
Vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) are well-known factors that induce neovascularization in many tumors. The molecular mechanisms that regulate tumor angiogenesis in human chondrosarcoma are not clear. We assessed in this work the angiogenic activities of a human chondrosarcoma cell line (OUMS-27) in vivo and… CONTINUE READING