Human carcinoma cells express receptors for distinct domains of thrombospondin.

@article{Yabkowitz1991HumanCC,
  title={Human carcinoma cells express receptors for distinct domains of thrombospondin.},
  author={Rachel Yabkowitz and Vishva M. Dixit},
  journal={Cancer research},
  year={1991},
  volume={51 6},
  pages={1645-50}
}
Thrombospondin (TSP), an adhesive glycoprotein, is incorporated into the extracellular matrix, mediates cell attachment and spreading, chemotaxis, haptotaxis, and may participate in the directed movement of cells in metastasis. Evidence from several model systems suggests that these functions may be mediated by different domains within the TSP molecule. Radioligand binding assays on 11B squamous carcinoma cells with 125I-Radioligand binding assays on 11B squamous carcinoma cells with 125I-TSP… CONTINUE READING