Human calcium-sensing receptor can be suppressed by antisense sequences.

Abstract

We have evaluated the ability of an antisense cDNA sequence, directed to the amino-terminus of the human calcium-sensing receptor (CaR), to reduce the expression and function of an EGFP-tagged CaR (CaR-EGFP) in HEK293 cells. Confocal microscopy and Western blot analysis showed a significant and selective reduction of the expression of CaR-EGFP by the… (More)

Topics

Cite this paper

@article{MaldonadoPrez2003HumanCR, title={Human calcium-sensing receptor can be suppressed by antisense sequences.}, author={David Maldonado-P{\'e}rez and Gerda Breitwieser and Lucio Gama and Austin C. Elliott and Donald T. Ward and Daniela M. dos R. Riccardi}, journal={Biochemical and biophysical research communications}, year={2003}, volume={311 3}, pages={610-7} }