Human bone morphogenetic protein-7 does not counteract aristolochic acid-induced renal toxicity.


Aristolochic acids (AA) are nephrotoxic and profibrotic agents, leading to chronic kidney disease. As some controversial studies have reported a nephroprotective effect of exogenous recombinant human bone morphogenetic protein (rhBMP)-7 in several models of renal fibrosis, we investigated the putative effect of rhBMP-7 to prevent progressive… (More)
DOI: 10.1002/jat.3116


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