Human bone marrow stromal cells protect prostate cancer cells from TRAIL-induced apoptosis.

Abstract

UNLABELLED Tumor-derived OPG has recently been shown to protect prostate cancer cells from apoptosis. This study has confirmed that bone marrow stromal cell-derived OPG also suppresses cytokine-induced apoptosis in this tumor type, suggesting that it may be the presence of bone-derived OPG that is responsible for the observed preference of these cells in… (More)

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