Human bone marrow stromal cells and skin fibroblasts inhibit natural killer cell proliferation and cytotoxic activity.

@article{Pradier2011HumanBM,
  title={Human bone marrow stromal cells and skin fibroblasts inhibit natural killer cell proliferation and cytotoxic activity.},
  author={Amandine Pradier and Jakob Robert Passweg and Jean Villard and Vincent Kindler},
  journal={Cell transplantation},
  year={2011},
  volume={20 5},
  pages={681-91}
}
Mesenchymal stromal cells (MSCs) are potent immunomodulators that have successfully been used to circumvent various types of inflammations, including steroid-resistant graft-versus-host disease. Although initially believed to be restricted to multipotent MSCs, this immunoregulatory function is shared with differentiated cells from the mesenchymal lineage such as skin fibroblasts (SFs). Mesenchymal cell-induced immunoregulation is so potent that it may allow the reactivation of dormant… CONTINUE READING

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