Human blood BDCA-1 dendritic cells differentiate into Langerhans-like cells with thymic stromal lymphopoietin and TGF-β.

Abstract

The ontogeny of human Langerhans cells (LCs) remains poorly characterized, in particular the nature of LC precursors and the factors that may drive LC differentiation. Here we report that thymic stromal lymphopoietin (TSLP), a keratinocyte-derived cytokine involved in epithelial inflammation, cooperates with transforming growth factor (TGF)-β for the… (More)
DOI: 10.1182/blood-2014-04-568311

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@article{MartnezCingolani2014HumanBB, title={Human blood BDCA-1 dendritic cells differentiate into Langerhans-like cells with thymic stromal lymphopoietin and TGF-β.}, author={Carolina Mart{\'i}nez-Cingolani and Maximilien Grandclaudon and Marine Jeanmougin and Mabel Jouve and Rapha{\"{e}l Zollinger and Vassili Soumelis}, journal={Blood}, year={2014}, volume={124 15}, pages={2411-20} }