Human bladder cancer diagnosis using Multiphoton microscopy.

@article{Mukherjee2009HumanBC,
  title={Human bladder cancer diagnosis using Multiphoton microscopy.},
  author={Sushmita Mukherjee and James S. Wysock and Casey K. Ng and Mohammed Akhtar and Sven Perner and M Lee and Mark A. Rubin and Frederick R Maxfield and Watt W. Webb and Douglas S. Scherr},
  journal={Proceedings of SPIE--the International Society for Optical Engineering},
  year={2009},
  volume={7161}
}
At the time of diagnosis, approximately 75% of bladder cancers are non-muscle invasive. Appropriate diagnosis and surgical resection at this stage improves prognosis dramatically. However, these lesions, being small and/or flat, are often missed by conventional white-light cystoscopes. Furthermore, it is difficult to assess the surgical margin for negativity using conventional cystoscopes. Resultantly, the recurrence rates in patients with early bladder cancer are very high. This is currently… CONTINUE READING

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While miniaturization of the Multiphoton microscope into an endoscopic format is currently in progress , we present results here indicating that Multiphoton imaging ( using a bench - top Multiphoton microscope ) can indeed identify cancers in fresh , unfixed human bladder biopsies .
While miniaturization of the Multiphoton microscope into an endoscopic format is currently in progress , we present results here indicating that Multiphoton imaging ( using a bench - top Multiphoton microscope ) can indeed identify cancers in fresh , unfixed human bladder biopsies .
While miniaturization of the Multiphoton microscope into an endoscopic format is currently in progress , we present results here indicating that Multiphoton imaging ( using a bench - top Multiphoton microscope ) can indeed identify cancers in fresh , unfixed human bladder biopsies .
Multiphoton endoscopes offer a potential solution , allowing real time , non - invasive biopsies of the human bladder , as well as an up - close assessment of the resection margin .
Multiphoton endoscopes offer a potential solution , allowing real time , non - invasive biopsies of the human bladder , as well as an up - close assessment of the resection margin .
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