Human beta-defensins 2 and 3 demonstrate strain-selective activity against oral microorganisms.

@article{Joly2004HumanB2,
  title={Human beta-defensins 2 and 3 demonstrate strain-selective activity against oral microorganisms.},
  author={Sophie A Joly and Connie Maze and Paul B. McCray and Janet M. Guthmiller},
  journal={Journal of clinical microbiology},
  year={2004},
  volume={42 3},
  pages={1024-9}
}
Human beta-defensins 2 and 3 (HBD-2 and HBD-3) are inducible peptides present at sites of infection in the oral cavity. A few studies have reported broad-spectrum antimicrobial activity for both peptides. However, no comprehensive study has thoroughly investigated their potential against oral pathogens. The purpose of this study was to test the effectiveness of HBD-2 and HBD-3 against a collection of oral organisms (Actinobacillus actinomycetemcomitans, Fusobacterium nucleatum, Porphyromonas… CONTINUE READING

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