• DOI:10.1038/333816A0
Corpus ID: 12992106

Human basophil degranulation triggered by very dilute antiserum against IgE

@article{Davenas1988HumanBD,
  title={Human basophil degranulation triggered by very dilute antiserum against IgE},
  author={E. Davenas and F. Beauvais and J. Amara and M. Oberbaum and B. Robinzon and A. Miadonnai and A. Tedeschi and B. Pomeranz and P. Fortner and P. Belon and J. Sainte-Laudy and B. Poitevin and J. Benveniste},
  journal={Nature},
  year={1988},
  volume={333},
  pages={816-818}
}

• E. Davenas, F. Beauvais, +10 authors J. Benveniste
• Published 1988
• Chemistry, Medicine
• Nature

When human polymorphonuclear basophils, a type of white blood cell with antibodies of the immunoglobulin E (IgE) type on its surface, are exposed to anti-IgE antibodies, they release histamine from their intracellular granules and change their staining properties. The latter can be demonstrated at dilutions of anti-IgE that range from 1 x 10(2) to 1 x 10(120); over that range, there are successive peaks of degranulation from 40 to 60% of the basophils, despite the calculated absence of any anti… Expand

View on Springer

oocities.org

Save to Library

Create Alert

Cite

Launch Research Feed