Human arthritic synovial fluid influences proteoglycan biosynthesis and degradation in organ culture of bovine nasal cartilage.

@article{Saxne1988HumanAS,
  title={Human arthritic synovial fluid influences proteoglycan biosynthesis and degradation in organ culture of bovine nasal cartilage.},
  author={Tore Saxne and Dick Heineg{\aa}rd and Frank A. Wollheim},
  journal={Collagen and related research},
  year={1988},
  volume={8 3},
  pages={233-47}
}
The influence of synovial fluid and serum from patients with inflammatory joint disease on proteoglycan metabolism was studied in organ culture of bovine nasal cartilage. Proteoglycan biosynthesis, i.e. incorporation of [35S]-sulphate, was reduced after addition of synovial fluid from rheumatoid arthritis and reactive arthritis patients. Also some… CONTINUE READING