Human antibody responses to vaccinia virus D 8 1 Structure-function characterization of three human antibodies targeting the vaccinia virus adhesion molecule D 8


Vaccinia virus (VACV) envelope protein D8 is one of three glycosaminoglycan adhesion molecules and binds to the linear polysaccharide chondroitin sulfate (CS). D8 is also a target for neutralizing antibody responses that are elicited by the smallpox vaccine, which has enabled the first eradication of a human viral pathogen and is a useful model for studying… (More)

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