• DOI:10.1038/nri1266
Corpus ID: 30584218

Human antibody–Fc receptor interactions illuminated by crystal structures

@article{Woof2004HumanAR,
  title={Human antibody–Fc receptor interactions illuminated by crystal structures},
  author={J. M. Woof and D. Burton},
  journal={Nature Reviews Immunology},
  year={2004},
  volume={4},
  pages={89-99}
}

J. M. Woof, D. Burton

Published 2004

Biology, Medicine

Nature Reviews Immunology

Immunoglobulins couple the recognition of invading pathogens with the triggering of potent effector mechanisms for pathogen elimination. Different immunoglobulin classes trigger different effector mechanisms through interaction of immunoglobulin Fc regions with specific Fc receptors (FcRs) on immune cells. Here, we review the structural information that is emerging on three human immunoglobulin classes and their FcRs. New insights are provided, including an understanding of the antibody… CONTINUE READING

View on Springer

ncbi.nlm.nih.gov

Save to Library

Create Alert

Cite

Launch Research Feed