Human anti-mouse antibody response in cancer patients following single low-dose injections of radiolabeled murine monoclonal antibodies.

Abstract

We examined the human anti-mouse antibody (HAMA) response in 61 cancer patients following a single, diagnostic injection of any one of ten 111In conjugated murine monoclonal antibodies. Between 1 and 22 mg of antibody containing 1-5 mCi 111In was administered. The populations studied included 30 patients with colorectal carcinoma (four different antibodies… (More)

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@article{Dillman1994HumanAA, title={Human anti-mouse antibody response in cancer patients following single low-dose injections of radiolabeled murine monoclonal antibodies.}, author={Robert Owen Dillman and Daniel L. Shawler and Tonya McCallister and Shravanti Halpern}, journal={Cancer biotherapy}, year={1994}, volume={9 1}, pages={17-28} }