Human anterolateral entorhinal cortex volumes are associated with cognitive decline in aging prior to clinical diagnosis

@article{Olsen2017HumanAE,
  title={Human anterolateral entorhinal cortex volumes are associated with cognitive decline in aging prior to clinical diagnosis},
  author={Rosanna K. Olsen and Lok-Kin Yeung and Alix Noly-Gandon and Maria C. D'Angelo and Morgan D. Barense},
  journal={Neurobiology of Aging},
  year={2017},
  volume={57},
  pages={195-205}
}
We investigated whether older adults without subjective memory complaints, but who present with cognitive decline in the laboratory, demonstrate atrophy in medial temporal lobe (MTL) subregions associated with Alzheimer's disease. Forty community-dwelling older adults were categorized based on Montreal Cognitive Assessment (MoCA) performance. Total gray/white matter, cerebrospinal fluid, and white matter hyperintensity load were quantified from whole-brain T1-weighted and fluid-attenuated… CONTINUE READING
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