Human and rodent DNA sequence comparisons: a mosaic model of genomic evolution.

@article{Koop1995HumanAR,
  title={Human and rodent DNA sequence comparisons: a mosaic model of genomic evolution.},
  author={Ben F. Koop},
  journal={Trends in genetics : TIG},
  year={1995},
  volume={11 9},
  pages={
          367-71
        }
}
Three patterns of DNA sequence conservation have been identified from five human and rodent genomic sequence comparisons. First, a divergent pattern was observed in the noncoding sequences of the beta-globin and gamma-crystallin gene clusters, and second, a highly conserved pattern was observed in the noncoding regions of the T cell receptor C alpha-C delta, and the alpha- and beta-myosin-heavy-chain genes. A third, mixed pattern has also been found in the immunoglobulin IgH C mu-C delta gene… CONTINUE READING
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