Human and rat skeletal muscle adaptations to spinal cord injury.

  title={Human and rat skeletal muscle adaptations to spinal cord injury.},
  author={Chris M. Gregory and Krista Vandenborne and Michael J. Castro and Gary A. Dudley},
  journal={Canadian journal of applied physiology = Revue canadienne de physiologie appliquee},
  volume={28 3},
Results of studies of rodent skeletal muscle plasticity are often extrapolated to humans. However, responses to "disuse" may be species specific, in part because of different inherent properties of anatomically similar muscles. Thus, this study quantified human and rat m. vastus lateralis (VL) fiber adaptations to 11 weeks of spinal cord injury (SCI). The m. VL was taken from 8 young (54 d) male Charles River rats after T-9 laminectomy (n = 4) or sham surgery (n = 4). In addition, the m. VL was… CONTINUE READING


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