Human and murine obliterative bronchiolitis in transplant.

  title={Human and murine obliterative bronchiolitis in transplant.},
  author={John F Mcdyer},
  journal={Proceedings of the American Thoracic Society},
  volume={4 1},
  • John F Mcdyer
  • Published 2007 in Proceedings of the American Thoracic Society
Obliterative bronchiolitis is a devastating illness that limits the long-term success of lung transplantation. Its high prevalence and overall poor response to current therapeutic measures demands further research to elucidate pathogenic mechanisms. Toward this goal, there is a role for animal models to study the mechanisms of obliterative bronchiolitis, such as the murine heterotopic tracheal allograft model. This review compares the tracheal allograft model to human obliterative bronchiolitis… CONTINUE READING

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