Human and murine model cell lines for dendritic cell biology evaluated.

@article{Helden2008HumanAM,
  title={Human and murine model cell lines for dendritic cell biology evaluated.},
  author={Suzanne F. G. van Helden and Frank N. van Leeuwen and Carl G. Figdor},
  journal={Immunology letters},
  year={2008},
  volume={117 2},
  pages={191-7}
}
Dendritic cells (DCs) are specialized antigen presenting cells that link innate and adaptive immune responses. As key mediators of T cell dependent immunity, DCs are considered primary targets for initiating immune responses in infectious diseases and cancer. Conversely, DCs can also play an important role in the induction of tolerance in organ transplantation, autoimmune disorders and allergy. While DCs have been used in clinical trials worldwide during the past decade, many of the highly… CONTINUE READING