Human and mouse macrophage-inducible C-type lectin (Mincle) bind Candida albicans.

@article{Bugarcic2008HumanAM,
  title={Human and mouse macrophage-inducible C-type lectin (Mincle) bind Candida albicans.},
  author={Andrea Bugarcic and Kelly J. Hitchens and Anthony G. Beckhouse and Christine A. Wells and Robert B. Ashman and Helen Blanchard},
  journal={Glycobiology},
  year={2008},
  volume={18 9},
  pages={679-85}
}
Candida albicans is a causative agent in mycoses of the skin, oral cavity, and gastrointestinal tract. Identification of receptors, and their respective ligands, that are engaged by immune cells when in contact with C. albicans is crucial for understanding inflammatory responses leading to invasive candidiasis. Mincle is a recently identified macrophage-expressed receptor that is important for host responses to C. albicans. The carbohydrate-recognition domain of human and mouse Mincle were… CONTINUE READING
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